产品货号:
Z36193
中文名称:
PCSK9抗体
英文名称:
Anti-PCSK9 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PCSK9 Antibody |
指标别名 | FH3;HCHOLA3;LDLCQ1;NARC 1;NARC1;PC9;PCSK9;Proprotein convertase 9 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | PCSK9 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human PCSK9 |
实际分子量 | 62,78KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Proprotein convertase subtilisin/kexin type 9,also known as PCSK9,is an enzyme that in humans is encoded by the PCSK9 gene.This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family.By genomic sequence analysis,PCSK9 was mapped to chromosome 1p32.This gene is a crucial player in the regulation of plasma cholesterol homeostasis.It may prevent the recycling of LDLR from endosomes to the cell surface or direct it to lysosomes for degradation.PCSK9 can induce ubiquitination of LDLR leading to its subsequent degradation.This gene is involved in the disposal of non-acetylated intermediates of BACE1 in the early secretory pathway. |
Uniprot ID | Q8NBP7 |
基因名全称 | Proprotein convertase subtilisin/kexin type 9 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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